DNA methylation

Peripheral blood DNA methylation partially reports on immune cell type composition in the frontal brain
Using matched frontal brain and peripheral blood samples, this study shows that blood DNA methylation profiles partially inform on immune cell type proportions in the brain, consistent with a link between peripheral and central nervous system immune function.
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RAMEN: Dissecting individual, additive and interactive gene-environment contributions to DNA methylome variability in cord blood
RAMEN, an R package that dissects the individual, additive and interactive contributions of genetic variants and environmental exposures to DNA methylation variability, applied to cord blood samples from the CHILD and PREDO cohorts.
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RAMEN: Dissecting individual, additive and interactive gene-environment contributions to DNA methylome variability in cord blood
Biological sex impacts immune cell proportions and epigenetic profiles in the developing pediatric immune system
DNA methylation-based analysis of whole blood from the CHILD cohort at ages one and five reveals age- and sex-associated differences in immune cell proportions and epigenetic profiles during early childhood, prior to puberty.
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Advancing Pediatric and Longitudinal DNA Methylation Studies with CellsPickMe, an Integrated Blood Cell Deconvolution Method
CellsPickMe, an R package for reference-based blood cell deconvolution from DNA methylation data that integrates cord and adult references, improving accuracy in cord, pediatric and adult blood samples for longitudinal birth cohort studies.
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