Progranulin

Progranulin genetic variant rs5848 displays ancestry-specific associations with Alzheimer's disease
Characterization of the GRN cis-regulatory region and ancestry-specific analyses of the Alzheimer’s Disease Sequencing Project reveal that the common progranulin variant rs5848 is associated with Alzheimer’s disease only in East Asian ancestry.
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FTD-associated behavioural and transcriptomic abnormalities in ‘humanized’progranulin-deficient mice: A novel model for progranulin-associated FTD
Generation and in-depth characterization of a “humanized” mouse model of progranulin deficiency.
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FTD-associated behavioural and transcriptomic abnormalities in ‘humanized’progranulin-deficient mice: A novel model for progranulin-associated FTD